The UMMISCO Center for Central and East Africa, the National Tuberculosis Control Program (PNLT), MEDES (Toulouse, France) and Cameroon's Centre Pasteur have entered into an exemplary collaboration to set up a tuberculosis surveillance system. Deployed at 47 sites, EPICAM already enables individualized monitoring of the care of 65% patients registered in Cameroon, and improved circulation of information between all players (healthcare staff, epidemiologists and decision-makers). The system is based on the Imogene platform, an open-source software package that enables rapid generation of data collection applications using MDA (Model Driven Architecture) technology. EPICAM was one of the winners of the Agence Française de Développement (AFD) innovation prize in 2014. EPICAM represents a perfect example of collaboration between scientific disciplines, in which the model acts as a mediator between partners, enabling them to go beyond data collection and work on scenarios, thereby influencing public decision-making.